THE EFFECTS OF LISDEXAMFETAMINE DIMESYLATE ON EATING BEHAVIOUR AND HOMEOSTATIC, REWARD AND COGNITIVE PROCESSES IN WOMEN WITH BINGE-EATING SYMPTOMS: AN EXPERIMENTAL MEDICINE STUDY

Abstract Lisdexamfetamine dimesylate (LDX) is the only drug currently approved by the FDA for the treatment of Binge-Eating Disorder (BED), but little is known about the behavioural mechanisms that underpin the efficacy of LDX in treating BED.We examined the behavioural and neural effects of an acute dose of LDX (50 mg) in 22 women with binge-eatin

Diffraction methods are commonly used for the determination of the elastic lattice deformation and distortion from the displacement and broadening of the ornament ice cube molds diffraction peak.These methods enable researchers to measure stresses and elastic properties of polycrystalline materials.The main advantages of diffraction methods are the

In the treatment of neurological diseases, neuroregeneration is a contentious and challenging issue.Our understanding of the mechanisms related exm1996 to neuroregeneration in neuromyelitis optica spectrum disorders (NMOSDs) is currently restricted and there lack of effective treatment to promote neuroregeneration and repair.To enhance the knowledg

Given the unique expression patterns and revelations of its critical involvement in a host of neurological disorders, the TRPC1/4/5 subgroup has become an intense target of drug development, and some compounds are now in clinical trials.However, little is known about the exact subunit composition of this subfamily of TRPC channels in various native

Dehydrins belongs to a large group of highly hydrophilic proteins known as Late Embryogenesis Abundant (LEA) proteins.It is well know that dehydrins are intrinsically kinkalicious disordered plant proteins that accumulate during the late stages of embryogenesis and in response to abiotic stresses; however, the molecular mechanisms by which their fu